Statistical Issues in Long-term Followup Studies

Long-term followup studies of schizophrenia: editors' introduction.

What are the major long-term followup studies of schizophrenia from around the world? What have we learned about schizophrenia and its vicissitudes over a lifetime? Does the lifelong vantage point help us to identify the primary psychopathologic components of schizophrenia and to distinguish it from other forms of mental illness? What are the implications of the longitudinal perspective for red...

Statistical Issues in Farmworker Studies

Should hormesis, as Thayer et al. (2006) implied in the title of their letter in the November 2006 issue of Environmental Health Perspectives, be dismissed by scientists, regulators, and others as simply a new faithbased religion? No. Hormesis is a data-based biological reality, one that challenges the lowdose assumptions that currently drive risk assessment processes used by regulatory and pub...

A selective review of recent North American long-term followup studies of schizophrenia.

North American outcome studies of schizophrenia conducted within the past quarter century are reviewed if their minimum average followup is 10 years and they meet at least some modern design criteria. Ten such investigations are described and summarized. Taken as a whole, they demonstrate that schizophrenia can be a chronic disease whose outcome on the average is worse than that of other major ...

Key Issues in Designing Long-term Care Systems: A Response to Recent Commentaries

Long-term followup of dextranomer/hyaluronic acid injection for vesicoureteral reflux: late failure warrants continued followup.

PURPOSE Dextranomer/hyaluronic acid injection of ureteral orifices is a popular option in the treatment of vesicoureteral reflux, with success rates ranging from 69% to 89%. We found only 1 study that followed patients beyond the initial postoperative voiding cystourethrogram, which describes a 96% success rate at 2 to 5 years but defines success as "nondilating" reflux. We examined our dextran...